Erica Del Grosso
Angew. Chem. 2020, 59, 13238-13245 (link)
Read the latest paper of our collaboration with the Ricci-group on the chemically fuelled self-assembly of DNA nanotubes
Maria Cardona
Chem. Sci. 2020, 11, 1518 - 1522 (link)
The addition of ATP under dissipative conditions causes the selective transient upregulation of a chemical reaction.
Find out all about the importance of multivalency in biological and synthetic systems in this book edited by Jurriaan Huskens (University of Twente), Rainer Haag (Freie Universität Berlin), Bart Jan Ravoo (Universität Münster) and Leonard Prins.
Chemists have so far approached the understanding of biology by reducing complex events to simple reactions and interactions. However, despite decades of intense biomimetic research, it is currently still unclear which conditions are required for a mixture of chemicals to acquire the ability to grow, communicate, move, evolve... The key point is that these so-called emerging properties cannot be traced back to a single molecule, but, instead, are the product of an ensemble of molecules. Following a bottom-up approach, systems chemistry aims at understanding how properties emerge from molecular networks.
Supramolecular chemistry is rapidly moving into new territory in which the composition of a dynamic system is no longer determined by the relative thermodynamic stabilities of the components, but by the capacity of the components to populate high-energy states exploiting energy-dissipating processes. This capacity implies that such systems may store and transfer energy, which would bring us closer to implementing the marvelous properties of living systems in synthetic ones.
Molecular recognition processes and catalysis in Nature involve large and complex structures such as antibodies and enzymes. The multipoint interactions that develop between host and guest permit binding to occur with high affinity and selectivity. Also, large structures facilitate the installment of regulatory mechanisms for instance through the formation of multicomponent complexes or the contemporary binding of co-factors. Synthetic systems that match up to the size and complexity of proteins could enable such properties in a nonbiological context or, alternatively, could be integrated in biological networks.
2015 - ... Professor in Organic Chemistry, Padova
2011 - 2015 Associate Professor, Padova
2004 - 2011 Assistant Professor, Padova
2002 - 2003 Postdoc, Licini-group, Padova
2001 - 2002 Postdoc, Dervan-group, Caltech, Pasadena, USA
2001 PhD in Chemistry (cum laude), Advisor: David Reinhoudt
University of Twente, Netherlands
1997 Engineer in Chemical Technology
University of Twente, Netherlands
Leonard J. Prins (1974, Netherlands) is full professor of Organic Chemistry in the Department of Chemical Sciences at the University of Padova, Italy. He obtained his PhD-degree from the University of Twente, Netherlands with prof. David Reinhoudt in 2001. After postdoctoral research with prof. Peter Dervan at Caltech, Pasadena, USA and prof. Giulia Licini at the University of Padova, Italy he started his independent career in 2004 in Padova. He has been awarded the 2001 Backer-prize by the Royal Dutch Chemical Society and the 2009 Ciamician-medal by the Italian Chemical Society. In 2009 he was the recipient of an ERC Starting Grant. His current research interests are the application of multivalent systems for catalysis, chemical network reactivity, and chemical fuel-driven self-assembly.
MSc: Huaqiao University, China
Yingjuan's project is working on the new chemical fuels for driven self-assembly processes.
MSc: Xiamen University, China
My research project is about light-induced regulation of chemical functions of gold-nanoparticle-based systems.
PhD: Indian Association for the Cultivation of Science, India
Krishnendu is a Seal-of-Excellence fellow at UNIPD working on the project DiSC: Dissipative Self-Assembly of Chemical Nanoreactors
MSc: University of Padova, Italy.
Tommaso started his PhD in October 2020. His project deals with chemical fuel driven self-assembly.
Giulio Ragazzon (2018)
Researcher, University of Trieste, Italy
Flavio della Sala (2017)
Webb-group, University of Manchester, UK
Jack Chen (2017)
Lecturer, Auckland University of Technology, New Zealand
Subhabrata Maiti (2017)
Assistant Professor, IISER Mohali, India
Davide Zaramella (2014)
Eureka, Trento, Italy
Cristian Gobbo (2014)
Sipag Bisalta SpA, Trissino, Italy
Jealemy Galindo (2014)
Creoptix, Zurich, Switzerland
Christian Franceschini (2014)
F.I.S., Vicenza, Italy
Grégory Pieters (2012)
Researcher, CEA Saclay, Paris, France
Giulio Gasparini (2012)
Firmenich, Geneva, Switzerland
Renato Bonomi (2011)
ITIS 'A. Rossi', Vicenza, Italy
Patrizia Galzerano (2010)
Politecnico di Milano, Italy
Anna Sansone (2010)
Researcher, CNR-ISOF, Bologna, Italy
Sushmitha Chandrabhas (2020)
Jawaharlal Nehru Centre for Advanced Scientific Research, IndiaMaria Cardona (2018)
Senior Research Officer, Malta College
Carlos Leon Prieto (2018)
Villapharme Research, Murcia, Spain
Simona Neri (2016)
IRIS Technology Group, Barcelona, Spain
Cristian Pezzato (2015)
Ambizione-grantee, EPFL, Switzerland
Sergio Garcia Martin (2015)
Biosystems S.A., Barcelona, Spain
Alessandro Cazzolaro (2014)
Delmachem Srl, Bassano del Grappa, Italy
Davide Zaramella (2013)
Eureka, Trento, Italy
Matteo Graziani (2012)
Pharmacy Sartori, Breganze, Italy
Marta Dal Molin (2012)
DuPont, Geneva, Switzerland
Giovanni Zaupa (2009)
NewChem Srl, Verona, Italy
Giulio Gasparini (2009)
Firmenich, Geneva, Switzerland
Cristian Guarise (2008)
Fidia Farmaceutici SpA, Padova, Italy
Tommaso Marchetti (2020, CTF)
Gioele Cocco (2020, Materials Science)
Nicolò Filippi (2020, CTF)
Alessandro Cavasso (2020, Chemistry)
Giacomo Michielli (2019, CTF)
Maura Troiani (2018, Chemistry)
Elisa Ceresari (2017, CTF)
Andrea Bonanni (2017, CTF)
Marco Leoni (2017, Chemistry)
Oscar Ferrari (2015, Biotech)
Michela Salvi (2013, Chemistry)
Barbara Jelenkovic (2012, CTF)
Massimiliano Martinelli (2012, Biotech)
Stefano Corrà (2012, Chemistry)
Cristian Pezzato (2011, Chemistry)
Matteo Giuliari (2011, Chemistry)
Veronica Subissati (2011, CTF)
Marta Balasso (2011, CTF)
Matteo Graziani (2011, CTF)
Alessandro Cazzolaro (2010, CTF)
Federico Bettin (2008, Biotech)
Claudia Mora (2008, Chemistry)
Andrea Levorato (2007, CTF)
Elisa Saresin (2006, CTF)
Giulio Gasparini (2005, Chemistry)
Giovanni Zaupa (2005, Chemistry)
Istruzioni esame scritto in modo telematico (Giugno- Luglio 2020)
Istruzioni (PDF)
Capitoli Brown-Foote
Book chapters/paragraphs 5th edition
(PDF)
Theoria (PDF-unico)
1. presentazione corso (PDF)
2. acidi_basi (PDF)
3. nucleofilicità (PDF)
4. reagenti organometallici (PDF)
5. ossidazioni_reduzioni (PDF)
6. aromaticità (PDF)
7. areni policiclici e eterociclici (PDF)
8. addizione nucleofila al carbonile (PDF)
9. reazioni di addizione_eliminazione (PDF)
10. acidi carbossilic e derivati (PDF)
11. enols and enolate ions (PDF)
12. addizione nucleofila di enolati (PDF)
13. addizione coniugata (PDF)
Esercizi (PDF-unico)
1. esercizi - 01 (PDF)
2. esercizi - 02 (PDF)
3. esercizi - 03 (PDF)
4. esercizi - 04 (PDF)
5. esercizi - 05 (PDF)
6. esercizi - 06 (PDF)
7. esercizi - 07 (PDF)
8. esercizi - 08 (PDF)
9. esercizi - 09 (PDF)
10. esercizi - 10 (PDF)
11. esercizi - 11 (PDF)
Esempi di esame
1. Esame - 01 (PDF)
risposte
2. Esame - 02 (PDF)
risposte
I documenti sono a disposizione su Moodle.
Multivalent Molecular Systems for Innovative Application (MULTI-APP). ITN between the Universities of Padova (coordinator), Cambridge (Hunter), Oxford (Anderson), Berlin (Haag), Eindhoven (Brunsveld), Twente (Huskens) and Ravoo (Munster).
Innovative sensing systems based on signal amplification
Replication and Adaptation in Molecular Networks (READ). ITN beteen the Universities of Groningen (Otto), Padova (Prins), Be'er Sheva (Ashkenasy), EPFL (Severin), Bochum (Von Kiedrowski), St. Andrews (Philp) and Strassbourg (Giuseppone e Delsuc)
Dynamic Covalent Capture: Dynamic Chemistry for Biomolecular Recognition and Catalysis (DYCOCA).
ADDRESS
Department of Chemical Sciences
University of Padova
Via Marzolo 1, 35131 Padova
ITALY
CONTACTS
Email: leonard.prins@unipd.it
ORCID: 0000-0001-6664-822X
Phone: (+39) 049 8275251
Fax: (+39) 049 8275050